A. Vazquez-Mayagoitia and S.R. Horton and B.G. Sumpter and J. Sponer and J.E. Sponer and M. Fuentes-Cabrera
Ab-initio modeling of a possible prebiotic reaction favors ribose over other possible sugars.
Astrobiology, 11, 115-121 (2011)
Many of us like to munch from time to time into the big question. That of the origin of life. Frankly, my guess is that anyone who works with RNA at any level is always tickled, to varying levels, by the big question. The authors of the referenced paper show a detailed quantum mechanical Ab-intio study on a so-called "silicate-mediated formose reaction" which, they show, by energetically favoring arguments, prefers ribose over other sugary options.
Robert V Brown; Laurence H Hurley @ Uni. Arizona
A Review of Cases where DNA might act like RNA
Biochemical Society Transactions, 39, 635-640 (2011)
A fun review mainly concerning the G-quadruplex and how this, and other DNA conformations with loops, for example, might behave in a similar fashion to RNA. It´s interesting to see their reproduced graph of the relation between G-quadruplexes and cancer.
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