Taken from C&EN January 22, 2007
Gottesman et al. have found that silent genes are no longer silent. They believe that the resulting proteins will differ in shape due to the different dynamics of their folding. The "silent" genes will act as delayers, and so the final configurational state that proteins with the same aminoacid sequence will fold to, when different synonymous genes are coding for the same aminoacid, will be different.